Virginia Chachati
2 min readJun 18, 2021

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Hello, I am a pharmacist. As a healthcare professional it is my duty to tell patients that when starting an antidepressant their symptoms may get worse before they get better. I stress this point and never downplay that they are 'mild'. It's better that they know what is going to happen and build a support network or system around them in anticipation of it. There is a 1 or 2 week adjustment period for their receptors to adapt to the chemical changes induced by the medicine. Once they overcome this adjustment period (which some patients cannot handle and do indeed quit), they often feel better and will take the medicine for as long as they need. Then there will be a controlled, what we call 'step-down' from the treatment so they slowly come off it. Sometimes medicines are, as I have experienced, a short-term solution to stabilise people's mental health. The goal is not to become dependent on the medicine, it is to buy time while on the medicine to have the courage to try other techniques and eventually come off the medicine. As we have limited data (which is also quite old) on which antidepressant is the best for you and at what dose, it is difficult to get it right first time. I have had patients that try three or four different antidepressants (not at the same time). This needs to be normalised as common practise. Similarly, when a doctor sees you they may not diagnose you correctly first time. That's why we call it a "working diagnosis". You may need to see the same doctor several times before you are both satisfied that your health problem has been resolved. Or you may need to see a collection of other healthcare professionals. This is why specialists exist and it's the same for healthcare professionals that work with patients that need help with their mental health. Please do not lump all healthcare professionals into the same basket. Like all professions, there will be a spectrum of abilities or effort one takes when it comes to treating a patient. I feel a deep sense of care towards my patients and this is why I wrote this comment. Thank you for reading and I hope I was able to show you a different perspective to think about after reading this article.

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Virginia Chachati
Virginia Chachati

Written by Virginia Chachati

Pharmacist, medical copywriter, social media marketing, remote work.

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